If you've been exposed to asbestos and suspect that you may have asbestosis or mesothelioma, it's very important that you see a doctor who has experience dealing with asbestos related diseases as soon as possible. The doctor will determine a mesothelioma diagnosis by taking a full medical history and performing a series of diagnostic tests.
One of the reasons that mesothelioma is so deadly is that it is often not diagnosed until it has reached late stage malignancy. New tests and more sensitive instruments have made it possible to get a mesothelioma diagnosis earlier in the progress of the disease. As with most types of cancer, the earlier that it's caught, the more treatment options you'll have. The sooner you have a mesothelioma diagnosis, the sooner treatment can begin. Here's what you can expect if you see a doctor to pursue a mesothelioma diagnosis.
Medical History
The doctor or a nurse will take a complete medical history to determine the symptoms you're experiencing and discover any risk factors. The history will include questions about when and where you might have been exposed to asbestos in the past. Among the symptoms the doctor will be looking for are frequent, painful cough, difficulty breathing and a history of lung function problems like pneumonia, emphysema and bronchitis.
Physical Examination
The doctor will also do a physical examination to discover any symptoms of mesothelioma. The examination will include listening to your breathing and heartbeat, as well as feeling (palpating) your abdomen. Patients with mesothelioma often have fluid buildups, known as effusions, in the tissues and cavities around the heart, lungs or in the abdomen.
X-rays and Imaging Tests
The next step in making a mesothelioma diagnosis is usually a series of chest X-rays. The X-rays may show any thickening of the lung tissues, irregularities in and around the lungs and mineral deposits or calcifications on the lung or pleural tissues. X-rays will also show any fluid buildup around or in the lungs. Any of these can suggest a mesothelioma diagnosis.
The doctor may then order other imaging tests, specifically CT scans and MRI scans. Together, the CT and MRI can help doctors to locate any lesions or tumors, and determine the extent and stage of the cancer. The imaging tests will tell the doctors what they need to know to suggest a course of treatment or further diagnostic testing.
Tissue and Fluid Samples
Your doctor may also want to take samples of fluid from around your lungs, heart or abdomen to determine if there are cancerous cells in it. This is usually done by inserting a needle into your chest cavity and withdrawing a small amount of the fluid for testing. The doctor may also recommend doing this to relieve uncomfortable pressure on the lungs and make breathing easier.
If the X-rays or other images show abnormal areas, your doctor may also want to take a tissue sample to examine for cancerous cells. Getting a sample for biopsy used to invariably involve surgery, but newer methods and equipment make it possible to obtain tissue samples without actually opening your chest. Only your doctor can determine if these methods will be appropriate in your case.
A thoracoscopy is performed with the help of an instrument called a thoracoscope - a telescope like instrument connected to a video camera. The doctor will make a small incision in your chest and insert the thorascoscope through it into your chest cavity. The video camera will allow the doctor to view and examine the tumor without opening your entire chest. He or she can then use a small, specially designed forceps to collect tissue from the tumor for testing. Doctors may also use the occasion of a thoracoscopy to remove fluid surrounding the lungs or pericardium.
Two other methods use similar instruments to obtain tissue samples and view close-ups of tumors and tissue. In a bronchoscopy, the doctor will insert a flexible, lighted tube through your mouth and thread it down through your trachea into the bronchia to find any masses or growths that may indicate pleural mesothelioma. Mediastinoscopy uses a lighted tube that is inserted beneath the sternum and into the chest cavity to view the lymph nodes in that area and examine them for growths abnormal appearance. In both of those procedures, doctors can remove tissue samples for testing.
Surgery is the most invasive method used in determining a mesothelioma diagnosis, but is sometimes the only way to remove a larger sample of the tumor. In some cases, if the cancer is still localized enough, the doctors may remove the entire tumor
Minggu, 31 Oktober 2010
Signs and symptoms
Symptoms or signs of mesothelioma may not appear until 20 to 50 years (or more) after exposure to asbestos. Shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space (pleural effusion) are often symptoms of pleural mesothelioma.
Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and pain due to ascites (a buildup of fluid in the abdominal cavity). Other symptoms of Peritoneal Mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.
These symptoms may be caused by mesothelioma or by other, less serious conditions.
Mesothelioma that affects the pleura can cause these signs and symptoms:
* Chest wall pain
* Pleural effusion, or fluid surrounding the lung
* Shortness of breath
* Fatigue or anemia
* Wheezing, hoarseness, or cough
* Blood in the sputum (fluid) coughed up (hemoptysis)
In severe cases, the person may have many tumor masses. The individual may develop a pneumothorax, or collapse of the lung. The disease may metastasize, or spread, to other parts of the body.
Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. Symptoms include:
* Abdominal pain
* Ascites, or an abnormal buildup of fluid in the abdomen
* A mass in the abdomen
* Problems with bowel function
* Weight loss
In severe cases of the disease, the following signs and symptoms may be present:
* Blood clots in the veins, which may cause thrombophlebitis
* Disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs
* Jaundice, or yellowing of the eyes and skin
* Low blood sugar level
* Pleural effusion
* Pulmonary emboli, or blood clots in the arteries of the lungs
* Severe ascites
A mesothelioma does not usually spread to the bone, brain, or adrenal glands. Pleural tumors are usually found only on one side of the lungs.
Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and pain due to ascites (a buildup of fluid in the abdominal cavity). Other symptoms of Peritoneal Mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.
These symptoms may be caused by mesothelioma or by other, less serious conditions.
Mesothelioma that affects the pleura can cause these signs and symptoms:
* Chest wall pain
* Pleural effusion, or fluid surrounding the lung
* Shortness of breath
* Fatigue or anemia
* Wheezing, hoarseness, or cough
* Blood in the sputum (fluid) coughed up (hemoptysis)
In severe cases, the person may have many tumor masses. The individual may develop a pneumothorax, or collapse of the lung. The disease may metastasize, or spread, to other parts of the body.
Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. Symptoms include:
* Abdominal pain
* Ascites, or an abnormal buildup of fluid in the abdomen
* A mass in the abdomen
* Problems with bowel function
* Weight loss
In severe cases of the disease, the following signs and symptoms may be present:
* Blood clots in the veins, which may cause thrombophlebitis
* Disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs
* Jaundice, or yellowing of the eyes and skin
* Low blood sugar level
* Pleural effusion
* Pulmonary emboli, or blood clots in the arteries of the lungs
* Severe ascites
A mesothelioma does not usually spread to the bone, brain, or adrenal glands. Pleural tumors are usually found only on one side of the lungs.
What is Mesothelioma?
Mesothelioma, more precisely malignant mesothelioma, is a rare form of cancer that develops from the protective lining that covers many of the body's internal organs, the mesothelium. It is usually caused by exposure to asbestos.
Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the heart, the pericardium (a sac that surrounds the heart) or tunica vaginalis.
Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles, or they have been exposed to asbestos dust and fiber in other ways. It has also been suggested that washing the clothes of a family member who worked with asbestos can put a person at risk for developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases the risk of other asbestos-induced cancers. Compensation via asbestos funds or lawsuits is an important issue in mesothelioma (see asbestos and the law).
The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung. Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. Research about screening tests for the early detection of mesothelioma is ongoing.
Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the heart, the pericardium (a sac that surrounds the heart) or tunica vaginalis.
Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles, or they have been exposed to asbestos dust and fiber in other ways. It has also been suggested that washing the clothes of a family member who worked with asbestos can put a person at risk for developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases the risk of other asbestos-induced cancers. Compensation via asbestos funds or lawsuits is an important issue in mesothelioma (see asbestos and the law).
The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung. Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. Research about screening tests for the early detection of mesothelioma is ongoing.
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